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KPC-2-IN-2

KPC-2 Inhibitor

KPC-2-IN-2 is a potent inhibitor of Klebsiella pneumoniae carbapenemase (KPC-2), demonstrating a dissociation constant (Ki) of 0.038 μM. This compound effectively enhances the antimicrobial activity of cefotaxime against KPC-2 expressing Escherichia coli. KPC-2-IN-2 serves as a valuable tool in research focused on overcoming antibiotic resistance in Gram-negative bacteria.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3034185-71-9
Applications	KPC-2 Inhibitor
Formula	C₁₂H₁₀BN₃O₂S
Molecular Weight	271.10
SMILES	OB(C1=CC=CC(N2C=C(N=N2)C3=CSC=C3)=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.