KRAS G12D-IN-32

Catalog No.: A63657
KRAS G12D Inhibitor
KRAS G12D-IN-32 is a selective inhibitor of the KRAS G12D mutant protein, which plays a critical role in various oncogenic pathways. This compound is instrumental for investigating the molecular mechanisms underlying adenocarcinoma, colorectal cancer, and non-small cell lung cancer. Researchers can employ KRAS G12D-IN-32 to explore therapeutic strategies targeting KRAS mutations and to evaluate potential treatment responses in cancer models.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKRAS G12D-IN-32 is a selective inhibitor of the KRAS G12D mutant protein, which plays a critical role in various oncogenic pathways. This compound is instrumental for investigating the molecular mechanisms underlying adenocarcinoma, colorectal cancer, and non-small cell lung cancer. Researchers can employ KRAS G12D-IN-32 to explore therapeutic strategies targeting KRAS mutations and to evaluate potential treatment responses in cancer models.
Product Information
Catalog NumA63657
FormulaC34H35F3N6O3
Molecular Weight632.68
CAS Number2885261-76-5
SMILESFC1=C(C2=CC(O)=CC3=C2C(CC)=C(F)C=C3)N=C4C5=C1N=C(N=C5N(C[C@@]6([H])N[C@]7([H])CC6)[C@]7([H])CO4)OC[C@@]89N(CCC9)C[C@@H](C8)F
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