Fig. 1 · Structure

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KRFK

Cat. No. A84887 CAS 162290-78-0

TGF-β Agonist

KRFK is a TGF-β agonist peptide derived from thrombospondin-1 (TSP-1) that activates the TGF-β pathway. This compound enhances TGF-β-mediated signaling and its downstream effects, operating independently of TSP receptors, including CD47 and CD36. KRFK is ideally suited for research applications involving chronic ocular surface inflammatory disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 162290-78-0
Applications TGF-β Agonist
Formula C27H47N9O5
Molecular Weight 577.72
SMILES
[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](CCCCN)N)=O)CCCNC(=N)N)=O)C(N[C@@H](CCCCN)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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