Fig. 1 · Structure
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KSK67
sigma-2/H3 receptor Antagonist
KSK67 is a high-affinity dual antagonist of the sigma-2 and histamine H3 receptors, exhibiting Ki values of 3.2 nM for the H3 receptor and 101 nM for the sigma-2 receptor. This compound demonstrates significant potential in the study of nociceptive and neuropathic pain pathways. KSK67's unique receptor profile makes it a valuable tool for investigating the modulation of pain-related mechanisms in various research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2566715-93-1 |
| Applications | sigma-2/H3 receptor Antagonist |
| Formula | C22H27N3O2 |
| Molecular Weight | 365.47 |
| SMILES | O=C(C1CC1)C2=CC=C(OCCCN3CCN(C4=CC=NC=C4)CC3)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.