Fig. 1 · Structure
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KSQ-4279
USP1 Inhibitor
KSQ-4279 is a potent inhibitor of USP1, which is involved in regulating protein deubiquitination. By inhibiting USP1, KSQ-4279 induces genomic instability and enhances the efficacy of DNA-damaging agents. This compound holds great potential for research applications in cancer biology, particularly in understanding the mechanisms of tumor progression and response to therapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2446480-97-1 |
| Applications | USP1 Inhibitor |
| Formula | C27H25F3N8O |
| Molecular Weight | 534.54 |
| Synonyms | USP1-IN-1 |
| SMILES | FC(F)(C1=CN(C(C)C)C(C2=CC=C(CN3N=CC4=C3N=C(C5=C(C6CC6)N=CN=C5OC)N=C4)C=C2)=N1)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.