KT2-962

Catalog No.: A63206
TXA2 Receptor Antagonist
KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and a potent hydroxyl radical scavenger (IC50=500 nM). This compound has been shown to significantly reduce myocardial infarct size and the incidence of ventricular fibrillation. In a canine model of ischemia/reperfusion, KT2-962 demonstrated notable cardioprotective effects, making it valuable for research into myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases.
Grouped product items
Size Price Stock Qty
25mg
$2,035.00
In stock
50mg
$2,610.00
In stock
100mg
$3,440.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKT2-962 is a thromboxane A2 (TXA2) receptor antagonist and a potent hydroxyl radical scavenger (IC50=500 nM). This compound has been shown to significantly reduce myocardial infarct size and the incidence of ventricular fibrillation. In a canine model of ischemia/reperfusion, KT2-962 demonstrated notable cardioprotective effects, making it valuable for research into myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases.
Product Information
Catalog NumA63206
FormulaC23H25ClNNaO5S2
Molecular Weight518.02
CAS Number129648-96-0
SMILESO=S(C1=C2C=CC(C(C)C)=CC=C2C(CCCCNS(=O)(C3=CC=C(C=C3)Cl)=O)=C1)(O[Na])=O
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