KU-177

Name: KU-177
Brand: Adooq Bioscience
SKU: A37585
Rating: 5 (288 reviews)

Catalog No.: A37585

Aha1/Hsp90 Disruptor

KU-177 is an effective disruptor of the Aha1/Hsp90 complex. It inhibits Aha1-driven enhancement of Hsp90-dependent tau aggregation, demonstrating an IC50 of 4.08 μM in disrupting Aha1/Hsp90 interactions without affecting Hsp90's ATPase activity. This compound is applicable in research focused on tauopathies, providing valuable insights into neurodegenerative processes.

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KU-177 1160952-43-1 Aha1/Hsp90 Disruptor

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Grouped product items
Size	Price	Stock
1mg	$370.00	In stock
5mg	$875.00	In stock
10mg	$1,200.00	In stock
25mg	$1,790.00	In stock
Bulk Size	Bulk Discount

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Research use only. We do not sell to patients.

Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description	KU-177 is an effective disruptor of the Aha1/Hsp90 complex. It inhibits Aha1-driven enhancement of Hsp90-dependent tau aggregation, demonstrating an IC50 of 4.08 μM in disrupting Aha1/Hsp90 interactions without affecting Hsp90's ATPase activity. This compound is applicable in research focused on tauopathies, providing valuable insights into neurodegenerative processes.

Product Information

Catalog Num	A37585
Formula	C27H23NO8
Molecular Weight	489.47
CAS Number	1160952-43-1
SMILES	COC1=CC(C2=C(C=CC(C(NC3=CC4=CC=C(C(OC)=C4OC3=O)OC(C)=O)=O)=C2)OC)=CC=C1

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