Fig. 1 · Structure
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Kurasoin B
Protein Farnesyltransferase Inhibitor
Kurasoin B is a potent inhibitor of protein farnesyltransferase, exhibiting an IC50 of 58.7 μM. This compound is derived from the fungus Paecilomyces sp. FO-3684 and plays a critical role in the regulation of protein modification pathways. Kurasoin B is valuable for research applications focusing on cancer biology and signal transduction, particularly in studies investigating protein farnesylation and its implications in oncogenic processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 193696-42-3 |
| Applications | Protein Farnesyltransferase Inhibitor |
| Formula | C18H17NO2 |
| Molecular Weight | 279.33 |
| SMILES | O=C(CC1=CC=CC=C1)[C@@H](CC2=CNC3=C2C=CC=C3)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.