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L 363851

Neurokinin 2 Receptor Agonist

L 363851 is a potent agonist of the neurokinin 2 receptor, demonstrating a significant contractile response in tracheal smooth muscle tissue devoid of epithelium with an IC50 value of 3.2 nM. Additionally, it stimulates phosphoinositide hydrolysis with an IC50 of 36 μM. This compound is valuable for research applications focusing on respiratory physiology and neurogenic inflammation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	100807-53-2
Applications	Neurokinin 2 Receptor Agonist
Formula	C₃₈H₅₁N₇O₇S
Molecular Weight	749.92
SMILES	CSCC[C@@H](C(N)=O)NC([C@@H](N1C([C@@H](CC1)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H]3CCC(N3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.