Fig. 1 · Structure

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L-644698

hDP Agonist

L-644698 is a highly selective agonist of the human recombinant prostaglandin D2 (PGD2) receptor (hDP), exhibiting Ki values of 0.9 nM for hDP and significantly higher values for other receptors (hEP2, hEP3, hEP4). This compound stimulates cyclic AMP production with an EC50 of 0.5 nM, making it a valuable tool for researching PGD2 receptor signaling pathways and their implications in various biological processes. Its specificity and potency render L-644698 an essential reagent for studies aimed at understanding the role of hDP in physiological and pathological states.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 72313-41-8
Applications hDP Agonist
Formula C21H31NO4S
Molecular Weight 393.54
SMILES
O=C(C1=CC=C(C=C1)CCCC(SCC2=O)N2CCC(CCCCC)O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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