Fig. 1 · Structure
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L 657925
TXA2 Antagonist
L 657925 is a potent thromboxane A2 (TXA2) antagonist, selectively inhibiting TXA2-mediated signaling pathways. This compound effectively abolishes the ONO 11113-induced transient increase in intracellular calcium concentration, making it a valuable tool for studying TXA2-related physiological processes. Its application spans research into cardiovascular diseases and platelet function, contributing to a deeper understanding of thromboxane's role in vascular biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 122757-59-9 |
| Applications | TXA2 Antagonist |
| Formula | C21H21ClFNO2 |
| Molecular Weight | 373.85 |
| SMILES | FC1=CC=C(N(C2([H])C3([H])CCCC2CC(O)=O)CC4=CC=C(C=C4)Cl)C3=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.