L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, exhibiting high selectivity and potency. The compound consists of two enantiomers: (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid, with an IC50 of 0.27 nM, and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid, with an IC50 of 124 nM. L-657926 is utilized in research focused on thromboxane signaling pathways, cardiovascular disease studies, and the modulation of related biological processes.
L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, exhibiting high selectivity and potency. The compound consists of two enantiomers: (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid, with an IC50 of 0.27 nM, and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid, with an IC50 of 124 nM. L-657926 is utilized in research focused on thromboxane signaling pathways, cardiovascular disease studies, and the modulation of related biological processes.
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