L-659837

Name: L-659837
Brand: Adooq Bioscience
SKU: A62118
Rating: 5 (288 reviews)

Catalog No.: A62118

NK2 Receptor Antagonist

L-659837 is a selective antagonist of the neurokinin-2 (NK2) receptor, effectively inhibiting GR 64349-induced contraction. This compound serves as a valuable tool in the investigation of urinary bladder disorders, allowing researchers to explore its therapeutic potential in conditions like overactive bladder and related urinary dysfunctions.

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L-659837 125989-10-8 NK2 Receptor Antagonist

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Grouped product items
Size	Price	Stock
25mg	$1,780.00	In stock
50mg	$2,280.00	In stock
100mg	$2,960.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	L-659837 is a selective antagonist of the neurokinin-2 (NK2) receptor, effectively inhibiting GR 64349-induced contraction. This compound serves as a valuable tool in the investigation of urinary bladder disorders, allowing researchers to explore its therapeutic potential in conditions like overactive bladder and related urinary dysfunctions.

Product Information

Catalog Num	A62118
Formula	C40H52N8O7S
Molecular Weight	788.96
CAS Number	125989-10-8
Sequence	Cyclo(Gln-Trp-Phe-{(R)Gly(ANC-2)}-Leu-Met)
Sequence shortening	Cyclo(QWF-{(R)Gly(ANC-2)}-LM)
SMILES	C(C=1C=2C(NC1)=CC=CC2)C3C(=O)NC(CC4=CC=CC=C4)C(=O)NC5C(=O)N(CC5)C(CC(C)C)C(=O)NC(CCSC)C(=O)NC(CCC(N)=O)C(=O)N3

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