Fig. 1 · Structure

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L-687306

mAChR Agonist

L-687306 is a high-affinity partial agonist of the muscarinic M1 receptor, demonstrating significant activity in rat ganglia. Additionally, it acts as a competitive antagonist at M2 and M3 muscarinic receptors in guinea pig cardiac and ileal tissues, respectively. This compound is valuable for investigating muscarinic receptor reserve and exploring muscarinic signaling pathways in various physiological contexts.

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Specifications

Manufacturer Adooq Bioscience
Actions Partial Agonist
CAS Number 133444-98-1
Applications mAChR Agonist
Formula C11H15N3O
Molecular Weight 205.26
SMILES
[H][C@@]12[C@@H](C3=NC(C4CC4)=NO3)C[N@](CC2)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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