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L 689660 maleate

M1/M3 Muscarinic Receptors Agonist

L 689660 maleate is a selective agonist for M1 and M3 muscarinic receptors, exhibiting potent cholinomimetic activity. Specifically, it demonstrates full agonist properties at the M1 muscarinic receptor in the rat superior cervical ganglion with a pEC50 of 7.3. Additionally, L 689660 maleate effectively activates M3 receptors in the guinea pig ileum myenteric plexus-longitudinal muscle and trachea, with pEC50 values of 7.5 and 7.7, respectively. This compound is valuable for research applications targeting muscarinic receptor signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	144860-79-7
Applications	M1/M3 Muscarinic Receptors Agonist
Formula	C₁₅H₁₈ClN₃O₄
Molecular Weight	339.77
SMILES	ClC1=CN=CC(C2CN3CCC2CC3)=N1.O=C(/C=C\C(O)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.