L 689660 maleate is a selective agonist for M1 and M3 muscarinic receptors, exhibiting potent cholinomimetic activity. Specifically, it demonstrates full agonist properties at the M1 muscarinic receptor in the rat superior cervical ganglion with a pEC50 of 7.3. Additionally, L 689660 maleate effectively activates M3 receptors in the guinea pig ileum myenteric plexus-longitudinal muscle and trachea, with pEC50 values of 7.5 and 7.7, respectively. This compound is valuable for research applications targeting muscarinic receptor signaling pathways.
L 689660 maleate is a selective agonist for M1 and M3 muscarinic receptors, exhibiting potent cholinomimetic activity. Specifically, it demonstrates full agonist properties at the M1 muscarinic receptor in the rat superior cervical ganglion with a pEC50 of 7.3. Additionally, L 689660 maleate effectively activates M3 receptors in the guinea pig ileum myenteric plexus-longitudinal muscle and trachea, with pEC50 values of 7.5 and 7.7, respectively. This compound is valuable for research applications targeting muscarinic receptor signaling pathways.
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