L-703606

Catalog No.: A62142
Neurokinin1 Receptor Antagonist
L-703606 is a potent and selective antagonist of the Neurokinin-1 (NK1) receptor. This compound effectively inhibits NK1 receptor activity, making it a valuable tool for investigating the role of neurokinin signaling in various physiological processes, including gastric acid secretion. Its application extends to studies focusing on pain modulation, inflammation, and other neuropsychiatric conditions, providing insights into the therapeutic potential of targeting NK1 receptors.
Grouped product items
Size Price Stock Qty
25mg
$1,405.00
In stock
50mg
$1,790.00
In stock
100mg
$2,240.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionL-703606 is a potent and selective antagonist of the Neurokinin-1 (NK1) receptor. This compound effectively inhibits NK1 receptor activity, making it a valuable tool for investigating the role of neurokinin signaling in various physiological processes, including gastric acid secretion. Its application extends to studies focusing on pain modulation, inflammation, and other neuropsychiatric conditions, providing insights into the therapeutic potential of targeting NK1 receptors.
Product Information
Catalog NumA62142
FormulaC27H29IN2
Molecular Weight508.44
CAS Number144425-84-3
SMILESIC(C=CC=C1)=C1CN[C@@H](C2CCN3CC2)[C@@H]3C(C4=CC=CC=C4)C5=CC=CC=C5
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