Fig. 1 · Structure

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L-703606

Neurokinin1 Receptor Antagonist

L-703606 is a potent and selective antagonist of the Neurokinin-1 (NK1) receptor. This compound effectively inhibits NK1 receptor activity, making it a valuable tool for investigating the role of neurokinin signaling in various physiological processes, including gastric acid secretion. Its application extends to studies focusing on pain modulation, inflammation, and other neuropsychiatric conditions, providing insights into the therapeutic potential of targeting NK1 receptors.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 144425-84-3
Applications Neurokinin1 Receptor Antagonist
Formula C27H29IN2
Molecular Weight 508.44
SMILES
IC(C=CC=C1)=C1CN[C@@H](C2CCN3CC2)[C@@H]3C(C4=CC=CC=C4)C5=CC=CC=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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