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L-731120

Squalene Synthase Inhibitor

L-731120 is a potent inhibitor of squalene synthase (SQS), with an IC50 value of 260 nM. This compound effectively reduces cholesterol synthesis in the liver, making it a valuable tool for studying metabolic diseases, including hypercholesterolemia. Additionally, L-731120 may be utilized in research focused on infectious diseases due to its metabolic modulating effects.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2232226-16-1
Applications	Squalene Synthase Inhibitor
Formula	C₂₃H₃₂O₇
Molecular Weight	420.50
SMILES	O[C@@](CC(O)=O)([C@H](CCCCC/C(C)=C/[C@@H](CC1=CC=CC=C1)C)C(O)=O)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.