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L-731735

FPTase Inhibitor

L-731735 is a selective inhibitor of farnesyltransferase (FPTase), a crucial enzyme in the post-translational modification of proteins involved in Ras signaling pathways. This compound has demonstrated efficacy in inhibiting Ras-dependent cell transformation, making it a valuable tool for studies focused on cancer biology and therapeutic development. Research applications include investigating the role of farnesylation in tumorigenesis and evaluating potential FPTase-targeted interventions in cancer treatment.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	149756-20-7
Applications	FPTase Inhibitor
Formula	C₁₉H₄₀N₄O₄S
Molecular Weight	420.61
SMILES	OCC[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC[C@@H](NC[C@@H](N)CS)[C@@H](C)CC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.