Fig. 1 · Structure
Documents & Downloads
L-751788
Cat. No.
A69137
CAS
166174-54-5
5 alpha Reductase Inhibitor
L-751788 is a selective inhibitor of type I 5α-reductase, a key enzyme involved in steroid metabolism. This compound demonstrates significant potential in reducing dihydrotestosterone levels without adversely affecting fetal external genitalia, as evidenced by studies conducted in pregnant rhesus monkeys. L-751788 is valuable for research applications investigating disorders of androgen metabolism and related therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 166174-54-5 |
| Applications | 5 alpha Reductase Inhibitor |
| Formula | C26H36ClNO2 |
| Molecular Weight | 430.02 |
| SMILES | O=C1N([C@@]2(C[C@@H]([C@@]3([H])[C@@]4(C[C@@H](C[C@]4(CC[C@@]3([C@]2(CC1)C)[H])C)OC5=CC=C(C=C5)Cl)[H])C)[H])C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.