L-760735 is a selective NK1 receptor antagonist that demonstrates high affinity with an IC50 of 0.19 nM for human NK1 receptors. This compound exhibits notable anxiolytic and antidepressant-like effects, making it a valuable tool for research in anxiety and mood disorders. Its oral bioavailability further enhances its utility in preclinical studies.
L-760735 is a selective NK1 receptor antagonist that demonstrates high affinity with an IC50 of 0.19 nM for human NK1 receptors. This compound exhibits notable anxiolytic and antidepressant-like effects, making it a valuable tool for research in anxiety and mood disorders. Its oral bioavailability further enhances its utility in preclinical studies.
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