L-Asparagine-13C4,15N2,d3 monohydrate is a stable isotope-labeled form of L-Asparagine, featuring deuterium, 13C, and 15N isotopes. This amino acid is critical for leukemic cell survival and serves as a substrate for the enzyme L-Asparaginase, which induces asparagine and glutamine depletion. The action of L-Asparaginase notably disrupts RNA and DNA synthesis, leading to apoptosis in lymphoblasts, particularly affecting cells with low asparagine synthetase expression. L-Asparagine-13C4,15N2,d3 monohydrate is a valuable tool for research into acute lymphoblastic leukemia, aiding in biomarker studies and the development of targeted therapies.
L-Asparagine-13C4,15N2,d3 monohydrate is a stable isotope-labeled form of L-Asparagine, featuring deuterium, 13C, and 15N isotopes. This amino acid is critical for leukemic cell survival and serves as a substrate for the enzyme L-Asparaginase, which induces asparagine and glutamine depletion. The action of L-Asparaginase notably disrupts RNA and DNA synthesis, leading to apoptosis in lymphoblasts, particularly affecting cells with low asparagine synthetase expression. L-Asparagine-13C4,15N2,d3 monohydrate is a valuable tool for research into acute lymphoblastic leukemia, aiding in biomarker studies and the development of targeted therapies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
