Fig. 1 · Structure
Documents & Downloads
L-Asparagine-13C4,15N2 monohydrate
Stable Isotope
L-Asparagine-13C4,15N2 monohydrate is a stable isotope-labeled form of the amino acid L-Asparagine, incorporating four carbon-13 and two nitrogen-15 atoms. This compound serves as a key substrate for the enzyme L-Asparaginase, which is crucial in the treatment of leukemia by depleting asparagine levels and inhibiting cellular protein biosynthesis, particularly in lymphoblasts. Through asparagine elimination from the plasma, L-Asparaginase triggers suppression of RNA and DNA synthesis, leading to apoptosis in cancer cells, especially those with low expression of asparagine synthetase. L-Asparagine monohydrate can also serve as a valuable biomarker for research involving childhood acute lymphoblastic leukemia.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 202406-87-9 |
| Applications | Stable Isotope |
| Formula | 13C4H1015N2O4 |
| Molecular Weight | 156.09 |
| SMILES | [15NH2][13C]([13CH2][13C@H]([15NH2])[13C](O)=O)=O.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.