L-Asparagine-13C4 monohydrate is a stable isotope-labeled form of L-Asparagine, specifically designated for metabolic tracing applications. This amino acid is critical for leukemic cell survival and serves as a substrate for L-Asparaginase, an enzyme that depletes asparagine and glutamine, thereby inhibiting protein biosynthesis and inducing apoptosis in lymphoblasts. The utilization of L-Asparagine-13C4 can facilitate research into the mechanisms of acute lymphoblastic leukemia, making it a valuable tool for understanding cancer cell metabolism and exploring potential therapeutic strategies.
L-Asparagine-13C4 monohydrate is a stable isotope-labeled form of L-Asparagine, specifically designated for metabolic tracing applications. This amino acid is critical for leukemic cell survival and serves as a substrate for L-Asparaginase, an enzyme that depletes asparagine and glutamine, thereby inhibiting protein biosynthesis and inducing apoptosis in lymphoblasts. The utilization of L-Asparagine-13C4 can facilitate research into the mechanisms of acute lymphoblastic leukemia, making it a valuable tool for understanding cancer cell metabolism and exploring potential therapeutic strategies.
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