Fig. 1 · Structure
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L-Homopropargylglycine hydrochloride
PROTAC Linker
L-Homopropargylglycine hydrochloride serves as an alkyl chain-based PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This amino acid analog of methionine features an alkyne group, enabling efficient click chemistry with azide-containing Alexa Fluor for labeling and detection purposes. Its application in PROTAC development supports innovative approaches in targeted protein degradation research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 942518-19-6 |
| Applications | PROTAC Linker |
| Formula | C6H10ClNO2 |
| Molecular Weight | 163.60 |
| SMILES | C#CCC[C@H](N)C(O)=O.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.