Fig. 1 · Structure
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L-threo Lysosphingomyelin (d18:1)
S1P Receptor Agonist
L-threo Lysosphingomyelin (d18:1) is a bioactive sphingolipid that functions as a potent agonist of the S1P receptor. It exhibits effective activation of human S1P receptors, with EC50 values of 19.3 nM for hS1P1, 131.8 nM for hS1P3, and 313.3 nM for hS1P2. This compound is valuable in research applications related to cell signaling, immunology, and inflammation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 105615-55-2 |
| Applications | S1P Receptor Agonist |
| Formula | C23H49N2O5P |
| Molecular Weight | 464.62 |
| Synonyms | L-threo-Sphingosylphosphorylcholine |
| SMILES | O=P(OCC[N+](C)(C)C)(OC[C@H](N)[C@@H](O)/C=C/CCCCCCCCCCCCC)[O-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.