Fig. 1 · Structure
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LacCer (d18:1/16:0)
Sphingolipid
LacCer (d18:1/16:0) is a bioactive sphingolipid that primarily targets membrane microdomains, interacting with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). Its elevated levels are associated with insulin resistance, particularly noted in cattle, and it shows upregulation in models of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. LacCer (d18:1/16:0) serves as a valuable reagent for research into metabolic and neurodegenerative diseases, providing insights into sphingolipid metabolism and cell signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 4201-62-1 |
| Applications | Sphingolipid |
| Formula | C46H87NO13 |
| Molecular Weight | 862.18 |
| Synonyms | C16 Lactosylceramide (d18:1/16:0) |
| SMILES | OC[C@@H](O[C@H]([C@@H]([C@H]1O)O)OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCC)=O)[C@H]1O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.