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Lampalizumab
Lampalizumab (RG 7417) is a humanized monoclonal antibody designed to selectively target complement Factor D within the alternative complement pathway. By binding to an exosite, Lampalizumab effectively inhibits the access of Factor B to the active site, thereby modulating the pathway's activity. This antibody is primarily utilized in the study of age-related macular degeneration (AMD), providing a valuable tool for researchers exploring the pathophysiology and potential therapeutic interventions for this condition.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1278466-20-8 |
| Molecular Weight | 143800 |
| Synonyms | RG 7417; TNX 234; Anti-CFD Recombinant Antibody |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.