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Biological Activity
Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.5 mL | 77.5 mL | 155.01 mL |
| 0.5 mM | 3.1 mL | 15.5 mL | 31 mL |
| 1 mM | 1.55 mL | 7.75 mL | 15.5 mL |
| 5 mM | 0.31 mL | 1.55 mL | 3.1 mL |
*The above data is based on the productmolecular weight 645.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A20851 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 189060-13-7 |
| Formula | C33H41ClN2O9 |
| M. Wt | 645.14 |
| Purity | >98% |
| Synonyms | TAK-475, TAK475, TAK 475 |
| SMILES | O=C(O)CC1CCN(C(C[C@@H]2C(N(CC(C)(C)COC(C)=O)C3=CC=C(Cl)C=C3[C@@H](C4=CC=CC(OC)=C4OC)O2)=O)=O)CC1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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