Lapatinib-13C215N

Catalog No.: A26949
Stable Isotope
Lapatinib-13C215N is a stable isotope-labeled variant of Lapatinib, specifically featuring 13C and 15N isotopes. This compound acts as a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains, displaying IC50 values of 10.2 nM and 9.8 nM, respectively, against purified targets. It is valuable for research applications in understanding signaling pathways involved in cancer and for quantitative analysis in pharmacokinetic studies.
Grouped product items
Size Price Stock Qty
500µg
$330.00
In stock
1mg
$645.00
In stock
5mg
$2,655.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLapatinib-13C215N is a stable isotope-labeled variant of Lapatinib, specifically featuring 13C and 15N isotopes. This compound acts as a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains, displaying IC50 values of 10.2 nM and 9.8 nM, respectively, against purified targets. It is valuable for research applications in understanding signaling pathways involved in cancer and for quantitative analysis in pharmacokinetic studies.
Product Information
Catalog NumA26949
FormulaC3413C2H34ClFN315NO7S2
Molecular Weight756.24
CAS Number1246819-08-8
SMILESCC1=CC=C(C=C1)S(=O)(O)=O.FC2=CC(COC3=CC=C(NC4=NC=NC5=CC=C(C=C54)C6=CC=C(O6)C[15NH][13CH2][13CH2]S(C)(=O)=O)C=C3Cl)=CC=C2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2