Lapatinib-13C215N is a stable isotope-labeled variant of Lapatinib, specifically featuring 13C and 15N isotopes. This compound acts as a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains, displaying IC50 values of 10.2 nM and 9.8 nM, respectively, against purified targets. It is valuable for research applications in understanding signaling pathways involved in cancer and for quantitative analysis in pharmacokinetic studies.
Lapatinib-13C215N is a stable isotope-labeled variant of Lapatinib, specifically featuring 13C and 15N isotopes. This compound acts as a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains, displaying IC50 values of 10.2 nM and 9.8 nM, respectively, against purified targets. It is valuable for research applications in understanding signaling pathways involved in cancer and for quantitative analysis in pharmacokinetic studies.
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