Lapatinib-d4 tosylate is a deuterated form of Lapatinib, a highly effective inhibitor targeting the tyrosine kinase domains of ErbB-2 and EGFR. It demonstrates potent biological activity with IC50 values of 10.2 nM and 9.8 nM against purified EGFR and ErbB-2, respectively. This stable isotope-labeled compound is valuable in pharmacokinetic studies and can facilitate research in cancer biology, particularly in the context of targeted therapies for breast cancer.
Lapatinib-d4 tosylate is a deuterated form of Lapatinib, a highly effective inhibitor targeting the tyrosine kinase domains of ErbB-2 and EGFR. It demonstrates potent biological activity with IC50 values of 10.2 nM and 9.8 nM against purified EGFR and ErbB-2, respectively. This stable isotope-labeled compound is valuable in pharmacokinetic studies and can facilitate research in cancer biology, particularly in the context of targeted therapies for breast cancer.
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