Fig. 1 · Structure
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Lappaol F
Anti-Cancer Agent
Lappaol F selectively targets YAP, demonstrating powerful anti-cancer properties. This lignan has been shown to inhibit both YAP mRNA and protein levels, leading to significant tumor cell growth suppression through the induction of cell cycle arrest. Additionally, Lappaol F promotes apoptosis in cancer cells, contributing to its efficacy in inhibiting tumor growth. Derived from Arctium lappa Linne (Asteraceae), Lappaol F is a valuable reagent for cancer research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 69394-17-8 |
| Applications | Anti-Cancer Agent |
| Formula | C40H42O12 |
| Molecular Weight | 714.75 |
| SMILES | O=C1OC[C@H](CC2=CC(OC)=C(O[C@H](C3=CC=C(O)C(OC)=C3)[C@H]4CO)C4=C2)[C@H]1CC5=CC(OC)=C(O[C@H](C6=CC=C(O)C(OC)=C6)[C@H]7CO)C7=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.