Fig. 1 · Structure

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Laropiprant sodium

DP Receptor Antagonist

Laropiprant sodium is a potent and selective antagonist of the DP receptor, exhibiting Ki values of 0.57 nM for the DP receptor and 2.95 nM for the TP receptor. This compound is utilized in research to explore its effects on inflammatory processes and vascular function due to its role in modulating prostaglandin signaling. Its high selectivity makes it a valuable tool for investigating DP receptor-mediated pathways in various biological contexts.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 572874-50-1
Applications DP Receptor Antagonist
Formula C21H18ClFNNaO4S
Molecular Weight 457.88
Synonyms MK-0524 sodium
SMILES
O=S(C1=CC(F)=CC2=C1N(C3=C2CC[C@@H]3CC(O[Na])=O)CC4=CC=C(Cl)C=C4)(C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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