Fig. 1 · Structure
Documents & Downloads
Larsucosterol sodium
LXR Antagonist
Larsucosterol sodium is a potent liver X receptor (LXR) antagonist, functioning primarily through inhibition of LXR signaling pathways. This compound acts as a key regulator of lipid metabolism, effectively decreasing lipogenesis by modulating the expression of cholesterol biosynthesis-related genes. Research applications include studies on metabolic disorders, cholesterol homeostasis, and the role of LXR in lipid regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1174047-40-5 |
| Applications | LXR Antagonist |
| Formula | C27H45NaO5S |
| Molecular Weight | 504.70 |
| Synonyms | DUR-928 sodium |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)OS(=O)(O[Na])=O)=CC3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.