Fig. 1 · Structure
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Larsucosterol
LXR Antagonist
Larsucosterol, a cholesterol metabolite, acts as a potent liver X receptor (LXR) antagonist. This compound effectively reduces lipogenesis and inhibits cholesterol biosynthesis by decreasing mRNA levels associated with the sterol regulatory element-binding protein 1 (SREBP-1). Its regulatory role makes Larsucosterol valuable in research applications related to metabolic disorders and lipid regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 884905-07-1 |
| Applications | LXR Antagonist |
| Formula | C27H46O5S |
| Molecular Weight | 482.72 |
| Synonyms | DUR-928 |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)OS(=O)(O)=O)=CC3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.