Fig. 1 · Structure
Documents & Downloads
LCAHA
USP2a Inhibitor
LCAHA (LCA hydroxyamide) is a potent inhibitor of the deubiquitinase USP2a, demonstrating IC50 values of 9.7 μM and 3.7 μM in the Ub-AMC and Di-Ub assays, respectively. By inhibiting USP2a, LCAHA leads to the destabilization of Cyclin D1 and induces G0/G1 cell cycle arrest. This compound is invaluable for studies focused on cell cycle regulation and the role of deubiquitination in cancer biology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 117094-40-3 |
| Applications | USP2a Inhibitor |
| Formula | C24H41NO3 |
| Molecular Weight | 391.59 |
| Synonyms | LCA hydroxyamide |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NO)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.