LCB 2853 sodium

Catalog No.: A63298
TXA2/PGH2 Receptor Antagonist
LCB 2853 sodium is a potent antagonist of the thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor, demonstrating significant anti-aggregant and anti-vasospastic properties. This compound is useful for investigating cardiovascular diseases, including hypertension, by providing insights into the modulation of platelet aggregation and vascular response. Its role in cardiovascular research highlights its potential as a valuable tool in the study of related pathophysiological processes.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLCB 2853 sodium is a potent antagonist of the thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor, demonstrating significant anti-aggregant and anti-vasospastic properties. This compound is useful for investigating cardiovascular diseases, including hypertension, by providing insights into the modulation of platelet aggregation and vascular response. Its role in cardiovascular research highlights its potential as a valuable tool in the study of related pathophysiological processes.
Product Information
Catalog NumA63298
FormulaC21H23ClNNaO4S
Molecular Weight443.92
CAS Number141335-11-7
SMILESO=C(O[Na])CC1=CC=C(CC2(CNS(=O)(C3=CC=C(Cl)C=C3)=O)CCCC2)C=C1
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