Fig. 1 · Structure
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LDL-IN-4
LDL Oxidation Inhibitor
LDL-IN-4 is a selective inhibitor of human acyl-CoA:cholesterol acyltransferase-1 and -2, effectively targeting the oxidation of low-density lipoprotein (LDL). This compound demonstrates significant inhibitory activity against copper-mediated LDL oxidation, with an IC50 value of 3 μM. LDL-IN-4 exhibits anti-atherosclerotic properties, making it a valuable tool for research focused on cardiovascular health and lipid metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 615264-62-5 |
| Applications | LDL Oxidation Inhibitor |
| Formula | C27H27NO7 |
| Molecular Weight | 477.51 |
| SMILES | O=C(OCC1=CC=CC=C1)C[C@@H](C(OCC2=CC=CC=C2)=O)NC(CCC3=CC=C(O)C(O)=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.