Fig. 1 · Structure
Documents & Downloads
LDN-209929 dihydrochloride
Haspin Kinase Inhibitor
LDN-209929 dihydrochloride is a potent and selective inhibitor of haspin kinase, demonstrating an IC50 of 55 nM and 180-fold selectivity against DYRK2 (IC50 = 9.9 μM). This compound serves as a valuable tool for probing the roles of haspin kinase in cell proliferation and other biological processes. Its optimized structure enhances its efficacy in research applications, particularly in studying cell cycle regulation and cancer therapeutics.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1784281-97-5 |
| Applications | Haspin Kinase Inhibitor |
| Formula | C17H19Cl3N2OS |
| Molecular Weight | 405.77 |
| SMILES | NCCCSC1=C(C=C(Cl)C=C2)C2=NC3=CC=C(OC)C=C31.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.