LDN-214117

Catalog No.: A16096

ALK2 inhibitor

LDN-214117

LDN-214117 Chemical Structure

CAS NO. 1627503-67-6

LDN-214117 is a selective and potent ALK2 inhibitor. LDN-214117 inhibited ALK2 most, with a biochemical IC50 of 24 nM.

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5 mg
$60.00
10 mg
$110.00
50 mg
$450.00
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Biological Activity

LDN-214117 is a selective and potent ALK2 inhibitor. LDN-214117 inhibited ALK2 most, with a biochemical IC50 of 24 nM.
Targets
ALK2
24 nM
In vitro (25°C) DMSO 74 mg/mL (176.39 mM)
Water Insoluble
Ethanol 74 mg/mL (176.39 mM)
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.84 mL 119.18 mL 238.37 mL
0.5 mM 4.77 mL 23.84 mL 47.67 mL
1 mM 2.38 mL 11.92 mL 23.84 mL
5 mM 0.48 mL 2.38 mL 4.77 mL

*The above data is based on the productmolecular weight 419.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16096
Actions Inhibitor
CAS No. 1627503-67-6
Formula C25H29N3O3
M. Wt 419.52
Solubility DMSO
Purity >98%
Synonyms LDN214117, LDN 214117
SMILES COC1=C(OC)C(OC)=CC(C2=C(C)N=CC(C3=CC=C(N4CCNCC4)C=C3)=C2)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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