Fig. 1 · Structure
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Ledipasvir D-tartrate
HCV Inhibitor
Ledipasvir D-tartrate is a potent inhibitor of the hepatitis C virus (HCV) NS5A protein. It demonstrates impressive antiviral activity with EC50 values of 34 pM against HCV genotype 1a and 4 pM against genotype 1b replicon systems. This compound is significant for research applications focusing on the development of antiviral therapies targeting HCV.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1502654-87-6 |
| Applications | HCV Inhibitor |
| Formula | C53H60F2N8O12 |
| Molecular Weight | 1039.09 |
| Synonyms | GS-5885 D-tartrate |
| SMILES | O=C(OC)N[C@H](C(N([C@H](C1=NC=C(C2=CC(C(F)(F)C3=C4C=CC(C5=CC=C6N=C([C@H]7N(C([C@@H](NC(OC)=O)C(C)C)=O)[C@]8([H])CC[C@@]7([H])C8)NC6=C5)=C3)=C4C=C2)N1)C9)CC%109CC%10)=O)C(C)C.O[C@@H]([C@@H](C(O)=O)O)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.