Lenalidomide (CC-5013)

Catalog No.: A10522
Ubiquitin ligase inducer
Lenalidomide is a derivative of thalidomide. In vitro, lenalidomide has three main activities: direct anti-tumor effect, inhibition of the micro environment support for tumor cells, and immunomodulatory role. It induces tumor cell apoptosis directly and indirectly by inhibition of bone marrow stromal cell support, by anti-angiogenic and anti-osteoclastogenic effects, and by immunomodulatory activity.
Grouped product items
Product Name Price Stock Qty
Lenalidomide 50mg
$40.00
In stock
Lenalidomide 100mg
$54.00
In stock
Lenalidomide 250mg
$75.00
In stock
Lenalidomide 500mg
$98.00
In stock
Lenalidomide (CC-5013) 10mM * 1mL in DMSO
$62.00
In stock
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Adooq Products cited in reputable paper
Adooq's Lenalidomide (CC-5013) has been cited by 4 publications
  • Daniel A. Rauch, .et al. , Retrovirology, 2020, 17: 27 PMID: 32859220
  • A Hayano, .et al. , Int J Clin Oncol, 2019, 1-10 PMID: 30993483
  • Kumar R, .et al. , Mol Biol Rep, 2018, Oct 11 PMID: 30311125
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
  • Biological Activity
    Discription Lenalidomide is a derivative of thalidomide. In vitro, lenalidomide has three main activities: direct anti-tumor effect, inhibition of the micro environment support for tumor cells, and immunomodulatory role. It induces tumor cell apoptosis directly and indirectly by inhibition of bone marrow stromal cell support, by anti-angiogenic and anti-osteoclastogenic effects, and by immunomodulatory activity.
    Targets
    Target Value
    Product Information
    Catalog Num A10522
    Formula C13H13N3O3
    Molecular Weight 259.3
    CAS Number 191732-72-6
    SMILES C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
    Synonyms Revlimid
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 46 mg/mL (177.43 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40%PEG 300+5%Tween80+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 38.57 mL 192.83 mL 385.65 mL
    0.5 mM 7.71 mL 38.57 mL 77.13 mL
    1 mM 3.86 mL 19.28 mL 38.57 mL
    5 mM 0.77 mL 3.86 mL 7.71 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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