Fig. 1 · Structure
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Leptomerine
AChE Inhibitor
Leptomerine is an alkaloid derived from the stems of Esenbeckia leiocarpa Engl. that functions as an acetylcholinesterase (AChE) inhibitor. With an IC50 of 2.5 μM, it exhibits significant anticholinesterase activity, potentially contributing to therapeutic strategies for Alzheimer’s disease. This compound is valuable for research aimed at understanding cholinergic dysfunction and developing cognitive-enhancing therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 22048-97-1 |
| Applications | AChE Inhibitor |
| Formula | C13H15NO |
| Molecular Weight | 201.26 |
| SMILES | O=C1C=C(CCC)N(C)C2=C1C=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.