Leptosphaerodione is a potent inhibitor of the ubiquitin-proteasome system (UPS), isolated from the fungus Remotididymella sp. This compound exhibits significant cytotoxic effects in HeLa cells, with an IC50 value of 3.2 μM. Leptosphaerodione serves as a valuable tool for research applications related to cancer biology and the development of anti-tumor strategies.
Leptosphaerodione is a potent inhibitor of the ubiquitin-proteasome system (UPS), isolated from the fungus Remotididymella sp. This compound exhibits significant cytotoxic effects in HeLa cells, with an IC50 value of 3.2 μM. Leptosphaerodione serves as a valuable tool for research applications related to cancer biology and the development of anti-tumor strategies.
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