Fig. 1 · Structure
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Leucosceptoside A
Cat. No.
A42349
CAS
83529-62-8
PKCα Inhibitor
Leucosceptoside A is a phenylethanoid glycoside that functions as a selective inhibitor of Protein Kinase C alpha (PKCα). This compound demonstrates significant anti-hyperglycemic and anti-hypertensive effects and exhibits inhibitory activity against α-glucosidase, with an IC50 value of 19.0 μM. Leucosceptoside A is relevant for research into metabolic disorders and cardiovascular diseases, providing insights into therapeutic approaches targeting PKCα.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 83529-62-8 |
| Applications | PKCα Inhibitor |
| Formula | C30H38O15 |
| Molecular Weight | 638.61 |
| SMILES | COC(C=C1/C=C/C(O[C@H]([C@H](O[C@H]([C@@H]2O)OCCC3=CC(O)=C(C=C3)O)CO)[C@@H]2O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)=O)=C(C=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.