Levomilnacipran-d10 hydrochloride is a deuterium-labeled form of Levomilnacipran hydrochloride, functioning primarily as a serotonin and norepinephrine reuptake inhibitor. This compound exhibits potent activity against the human norepinephrine transporter (NET) and serotonin transporter (SERT), with IC50 values of 10.5 nM and 19.0 nM, respectively. Levomilnacipran-d10 hydrochloride is primarily used in research related to depression, providing a stable isotope variant for pharmacokinetic studies and metabolic tracing. Its ability to cross the blood-brain barrier enhances its relevance in neuropharmacological investigations.
Levomilnacipran-d10 hydrochloride is a deuterium-labeled form of Levomilnacipran hydrochloride, functioning primarily as a serotonin and norepinephrine reuptake inhibitor. This compound exhibits potent activity against the human norepinephrine transporter (NET) and serotonin transporter (SERT), with IC50 values of 10.5 nM and 19.0 nM, respectively. Levomilnacipran-d10 hydrochloride is primarily used in research related to depression, providing a stable isotope variant for pharmacokinetic studies and metabolic tracing. Its ability to cross the blood-brain barrier enhances its relevance in neuropharmacological investigations.
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