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Levomilnacipran

Serotonin/Norepinephrine Reuptake Inhibitor

Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) that effectively targets the human norepinephrine transporter (NET) and serotonin transporter (SERT), with IC50 values of 10.5 nM and 19.0 nM, respectively. This compound demonstrates significant antidepressant and anxiolytic properties, making it a valuable research tool for studying depression and anxiety disorders. As an active enantiomer of Milnacipran, Levomilnacipran can cross the blood-brain barrier, facilitating its utility in neurological studies. Levomilnacipran hydrochloride is ideal for investigating the mechanisms underlying mood regulation and the pharmacological effects of SNRIs.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	96847-54-0
Applications	Serotonin/Norepinephrine Reuptake Inhibitor
Formula	C₁₅H₂₂N₂O
Molecular Weight	246.35
Synonyms	(1S,2R)-Milnacipran; F2695
SMILES	O=C(N(CC)CC)[C@@]1([C@@H](C1)CN)C2=CC=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.