Fig. 1 · Structure
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Licoflavone A
Phosphatase Inhibitor
Licoflavone A is a flavonoid that serves as a selective inhibitor of protein tyrosine phosphatase-1B (PTP1B), exhibiting an IC50 of 54.5 μM. This compound is of particular interest in research related to glucose metabolism and insulin signaling, making it valuable for studies investigating diabetes and obesity. Its ability to modulate phosphatase activity positions Licoflavone A as a potential therapeutic agent in metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 61153-77-3 |
| Applications | Phosphatase Inhibitor |
| Formula | C20H18O4 |
| Molecular Weight | 322.35 |
| SMILES | O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)\C)C=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.