Fig. 1 · Structure
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Linopirdine dihydrochloride
Cat. No.
A68853
CAS
113168-57-3
TRPV1 Agonist
Linopirdine dihydrochloride is an agonist of the capsaicin receptor TRPV1, which plays a key role in nociception. This compound enhances intracellular calcium levels in HEK293 cells, leading to increased excitatory responses in mammalian nociceptors. Linopirdine dihydrochloride is valuable for research applications focused on pain mechanisms and sensory neuron function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 113168-57-3 |
| Applications | TRPV1 Agonist |
| Formula | C26H23Cl2N3O |
| Molecular Weight | 464.39 |
| Synonyms | DuP 996 dihydrochloride |
| SMILES | O=C1N(C2=CC=CC=C2)C3=C(C=CC=C3)C1(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.