Fig. 1 · Structure

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Liothyronine hydrochloride

TRα/TRβ Agonist

Liothyronine hydrochloride is an active form of thyroid hormone that functions as a selective agonist for thyroid hormone receptors TRα and TRβ. With dissociation constants (Kis) of 2.33 nM for both hTRα and hTRβ, it demonstrates potent biological activity. This compound is utilized in research applications focused on thyroid hormone signaling, metabolism studies, and related endocrine functions.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 6138-47-2
Applications TRα/TRβ Agonist
Formula C15H13ClI3NO4
Molecular Weight 687.43
Synonyms Triiodothyronine hydrochloride; 3,3',5-Triiodo-L-thyronine hydrochloride; T3 hydrochloride
SMILES
O=C([C@H](CC1=CC(I)=C(C(I)=C1)OC2=CC=C(C(I)=C2)O)N)O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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