Fig. 1 · Structure
Documents & Downloads
Liothyronine sodium hydrate
TRα/TRβ Agonist
Liothyronine sodium hydrate is an active form of thyroid hormone that acts as a potent agonist for thyroid hormone receptors TRα and TRβ. With binding affinities (Kis) of 2.33 nM for both human TRα and TRβ, this compound has significant biological activity in regulating gene expression related to metabolism and growth. It is suitable for research applications focused on thyroid hormone signaling, metabolic regulation, and related endocrine studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 345957-19-9 |
| Applications | TRα/TRβ Agonist |
| Formula | C15H12I3NO4.xH2O.Na |
| Synonyms | Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate |
| SMILES | N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC=C(O)C(I)=C2)C(O[Na])=O.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.